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Genetic alteration of human MYH6 is mimicked by SARS-CoV-2 polyprotein: mapping viral variants of cardiac interest

Acute cardiac injury has been observed in a subset of COVID-19 patients, but the molecular basis for this clinical phenotype is unknown. It has been hypothesized that molecular mimicry may play a role in triggering an autoimmune inflammatory reaction in some individuals after SARS-CoV-2 infection. H...

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Detalles Bibliográficos
Autores principales: Anand, Praveen, Lenehan, Patrick J., Niesen, Michiel, Yoo, Unice, Patwardhan, Dhruti, Montorzi, Marcelo, Venkatakrishnan, A. J., Soundararajan, Venky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935120/
https://www.ncbi.nlm.nih.gov/pubmed/35314694
http://dx.doi.org/10.1038/s41420-022-00914-9