Non-operative management after chemoradiotherapy plus consolidation or sandwich (induction with bevacizumab and consolidation) chemotherapy in patients with locally advanced rectal cancer: a multicentre, randomised phase II trial (NOMINATE trial)

INTRODUCTION: Total mesorectal excision (TME) and postoperative adjuvant chemotherapy following neoadjuvant chemoradiotherapy (CRT) is the standard treatment for locally advanced rectal cancer (LARC). However, neoadjuvant CRT has no recognised impact on reducing distant recurrence, and patients suff...

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Detalles Bibliográficos
Autores principales: Akiyoshi, Takashi, Shinozaki, Eiji, Taguchi, Senzo, Chino, Akiko, Hiratsuka, Makiko, Tominaga, Tetsuro, Nonaka, Takashi, Toda, Shigeo, Matoba, Shuichiro, Matsui, Shimpei, Okabayashi, Koji, Mukai, Toshiki, Hiyoshi, Yukiharu, Yamaguchi, Tomohiro, Nagasaki, Toshiya, Yamaguchi, Kensei, Ueno, Masashi, Kuroyanagi, Hiroya, Fukunaga, Yosuke, Ishizuka, Naoki, Konishi, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935173/
https://www.ncbi.nlm.nih.gov/pubmed/35304396
http://dx.doi.org/10.1136/bmjopen-2021-055140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935173/
https://www.ncbi.nlm.nih.gov/pubmed/35304396
http://dx.doi.org/10.1136/bmjopen-2021-055140

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