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Rapid Decline of Ceftazidime Resistance in Antibiotic-Free and Sublethal Environments Is Contingent on Genetic Background

Trade-offs of antibiotic resistance evolution, such as fitness cost and collateral sensitivity (CS), could be exploited to drive evolution toward antibiotic susceptibility. Decline of resistance may occur when resistance to other drug leads to CS to the first one and when compensatory mutations, or...

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Detalles Bibliográficos
Autores principales: Hernando-Amado, Sara, Laborda, Pablo, Valverde, José Ramón, Martínez, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935207/
https://www.ncbi.nlm.nih.gov/pubmed/35291010
http://dx.doi.org/10.1093/molbev/msac049