Mutations in Drosophila tRNA processing factors cause phenotypes similar to Pontocerebellar Hypoplasia

Mature transfer (t)RNAs are generated by multiple RNA processing events, which can include the excision of intervening sequences. The tRNA splicing endonuclease (TSEN) complex is responsible for cleaving these intron-containing pre-tRNA transcripts. In humans, TSEN copurifies with CLP1, an RNA kinas...

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Detalles Bibliográficos
Autores principales: Schmidt, Casey A., Min, Lucy Y., McVay, Michelle H., Giusto, Joseph D., Brown, John C., Salzler, Harmony R., Matera, A. Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935212/
https://www.ncbi.nlm.nih.gov/pubmed/35132432
http://dx.doi.org/10.1242/bio.058928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935212/
https://www.ncbi.nlm.nih.gov/pubmed/35132432
http://dx.doi.org/10.1242/bio.058928

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