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miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease

Background and Purpose: Recently, several abnormally regulated microRNAs (miRNAs) have been identified in patients with Alzheimer's disease (AD). The purpose of this study was to identify abnormally expressed miRNAs and to investigate whether they affect pathological changes in AD in the 5xFAD...

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Detalles Bibliográficos
Autores principales: Park, Hyunjun, Lee, Yeong-Bae, Chang, Keun-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935215/
https://www.ncbi.nlm.nih.gov/pubmed/35342350
http://dx.doi.org/10.7150/ijbs.66604