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Specific overexpression of SIRT1 in mesenchymal stem cells rescues hematopoiesis niche in BMI1 knockout mice through promoting CXCL12 expression

Osteoblastic lineage cells (OBCs) are bone-building cells and essential component of hematopoietic niche, but mechanisms whereby bone-building and hematopoiesis-supportive activities of OBCs could be regulated simultaneously remain largely unknown. Here we found that B cell-specific Moloney murine l...

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Detalles Bibliográficos
Autores principales: Li, Jinbo, Li, Xing, Sun, Wen, Zhang, Jiao, Yan, Quanquan, Wu, Jun, Jin, Jianliang, Lu, Ruinan, Miao, Dengshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935221/
https://www.ncbi.nlm.nih.gov/pubmed/35342358
http://dx.doi.org/10.7150/ijbs.63876