HB-EGF induces mitochondrial dysfunction via estrogen hypersecretion in granulosa cells dependent on cAMP-PKA-JNK/ERK-Ca(2+)-FOXO1 pathway

Polycystic ovarian syndrome (PCOS) is one of the most prevalent endocrinopathies and the leading cause of anovulatory infertility, but its pathogenesis remains elusive. Although HB-EGF is involved in ovarian cancer progression, there is still no clarity about its relevance with PCOS. The present stu...

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Detalles Bibliográficos
Autores principales: Huang, Ji-Cheng, Duan, Cui-Cui, Jin, Shan, Sheng, Chuan-Bo, Wang, Yu-Si, Yue, Zhan-Peng, Guo, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935223/
https://www.ncbi.nlm.nih.gov/pubmed/35342363
http://dx.doi.org/10.7150/ijbs.69343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935223/
https://www.ncbi.nlm.nih.gov/pubmed/35342363
http://dx.doi.org/10.7150/ijbs.69343

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