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Forsythoside A Mitigates Alzheimer's-like Pathology by Inhibiting Ferroptosis-mediated Neuroinflammation via Nrf2/GPX4 Axis Activation

Ferroptosis and neuroinflammation play crucial roles in Alzheimer's disease (AD) pathophysiology. Forsythoside A (FA), the main constituent of Forsythia suspensa (Thunb.) Vahl., possesses anti-inflammatory, antibacterial, antioxidant, and neuroprotective properties. The present study aimed to i...

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Detalles Bibliográficos
Autores principales: Wang, Chunyue, Chen, Shanshan, Guo, Hangyu, Jiang, Hongbo, Liu, Honghan, Fu, Haoran, Wang, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935224/
https://www.ncbi.nlm.nih.gov/pubmed/35342364
http://dx.doi.org/10.7150/ijbs.69714