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Interleukin-17 programs liver progenitor cell transformation into cancer stem cells through miR-122 downregulation with increased risk of primary liver cancer initiation

Chronic inflammation is a key component in the development of virtually all types of primary liver cancers. However, how chronic inflammation potentiates or even may initiate liver parenchymal cell transformation remains unclear. Cancer stem cells (CSCs) represent an exciting target for novel antica...

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Detalles Bibliográficos
Autores principales: Gasmi, Imène, Machou, Camilia, Rodrigues, Aurélie, Brouillet, Arthur, Nguyen, Trung Cong, Rousseau, Benoit, Guillot, Adrien, Rodriguez, Christophe, Demontant, Vanessa, Ait-Ahmed, Yeni, Calderaro, Julien, Luciani, Alain, Pawlotsky, Jean-Michel, Lafdil, Fouad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935237/
https://www.ncbi.nlm.nih.gov/pubmed/35342340
http://dx.doi.org/10.7150/ijbs.70408