Ebselen enhances insulin sensitivity and decreases oxidative stress by inhibiting SHIP2 and protects from inflammation in diabetic mice

Ebselen, a multifunctional organoselenium compound, has been recognized as a potential treatment for diabetes-related disorders. However, the underlying mechanisms whereby ebselen regulates metabolic pathways remain elusive. We discovered that ebselen inhibits lipid phosphatase SHIP2 (Src homology 2...

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Detalles Bibliográficos
Autores principales: Polianskyte-Prause, Zydrune, Tolvanen, Tuomas A., Lindfors, Sonja, Kon, Kanta, Hautala, Laura C., Wang, Hong, Wada, Tsutomu, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Lehtonen, Sanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935241/
https://www.ncbi.nlm.nih.gov/pubmed/35342343
http://dx.doi.org/10.7150/ijbs.66314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935241/
https://www.ncbi.nlm.nih.gov/pubmed/35342343
http://dx.doi.org/10.7150/ijbs.66314

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