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A coarse-grained NADH redox model enables inference of subcellular metabolic fluxes from fluorescence lifetime imaging
Mitochondrial metabolism is of central importance to diverse aspects of cell and developmental biology. Defects in mitochondria are associated with many diseases, including cancer, neuropathology, and infertility. Our understanding of mitochondrial metabolism in situ and dysfunction in diseases are...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935353/ https://www.ncbi.nlm.nih.gov/pubmed/34806591 http://dx.doi.org/10.7554/eLife.73808 |