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Cerebrospinal Fluid Biomarkers in Autopsy-Confirmed Alzheimer Disease and Frontotemporal Lobar Degeneration

BACKGROUND AND OBJECTIVES: To determine how fully automated Elecsys CSF immunoassays for β-amyloid (Aβ) and tau biomarkers and an ultrasensitive Simoa assay for neurofilament light chain (NFL) correlate with neuropathologic changes of Alzheimer disease (AD) and frontotemporal lobar degeneration (FTL...

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Detalles Bibliográficos
Autores principales: Mattsson-Carlgren, Niklas, Grinberg, Lea T., Boxer, Adam, Ossenkoppele, Rik, Jonsson, Magnus, Seeley, William, Ehrenberg, Alexander, Spina, Salvatore, Janelidze, Shorena, Rojas-Martinex, Julio, Rosen, Howard, La Joie, Renaud, Lesman-Segev, Orit, Iaccarino, Leonardo, Kollmorgen, Gwendlyn, Ljubenkov, Peter, Eichenlaub, Udo, Gorno-Tempini, Maria Luisa, Miller, Bruce, Hansson, Oskar, Rabinovici, Gil Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935438/
https://www.ncbi.nlm.nih.gov/pubmed/35173015
http://dx.doi.org/10.1212/WNL.0000000000200040