GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products

BACKGROUND: Functional complexity of the eukaryotic mitochondrial proteome is augmented by independent gene acquisition from bacteria since its endosymbiotic origins. Mammalian homologs of many ancestral mitochondrial proteins have uncharacterized catalytic activities. Recent forward genetic approac...

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Detalles Bibliográficos
Autores principales: Smith, Andrew J., Advani, Jayshree, Brock, Daniel C., Nellissery, Jacob, Gumerson, Jessica, Dong, Lijin, Aravind, L., Kennedy, Breandán, Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935817/
https://www.ncbi.nlm.nih.gov/pubmed/35307029
http://dx.doi.org/10.1186/s12915-022-01267-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935817/
https://www.ncbi.nlm.nih.gov/pubmed/35307029
http://dx.doi.org/10.1186/s12915-022-01267-6

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