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The voltage-gated K(+) channel Kv1.3 modulates platelet motility and α(2)β(1) integrin-dependent adhesion to collagen

Kv1.3 is a voltage-gated K(+)-selective channel with roles in immunity, insulin-sensitivity, neuronal excitability and olfaction. Despite being one of the largest ionic conductances of the platelet surface membrane, its contribution to platelet function is poorly understood. Here we show that Kv1.3-...

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Detalles Bibliográficos
Autores principales: Wright, Joy R, Jones, Sarah, Parvathy, Sasikumar, Kaczmarek, Leonard K, Forsythe, Ian, Farndale, Richard W, Gibbins, Jonathan M, Mahaut-Smith, Martyn P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8935947/
https://www.ncbi.nlm.nih.gov/pubmed/34348571
http://dx.doi.org/10.1080/09537104.2021.1942818