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SARS-CoV-2 Spike Protein 1 Activates Microvascular Endothelial Cells and Complement System Leading to Platelet Aggregation

Microvascular thrombosis is associated with multiorgan failure and mortality in coronavirus disease 2019 (COVID-19). Although thrombotic complications may be ascribed to the ability of SARS-CoV-2 to infect and replicate in endothelial cells, it has been poorly investigated whether, in the complexity...

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Detalles Bibliográficos
Autores principales: Perico, Luca, Morigi, Marina, Galbusera, Miriam, Pezzotta, Anna, Gastoldi, Sara, Imberti, Barbara, Perna, Annalisa, Ruggenenti, Piero, Donadelli, Roberta, Benigni, Ariela, Remuzzi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936079/
https://www.ncbi.nlm.nih.gov/pubmed/35320941
http://dx.doi.org/10.3389/fimmu.2022.827146