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LncRNA-RMST Functions as a Transcriptional Co-regulator of SOX2 to Regulate miR-1251 in the Progression of Hirschsprung's Disease

Hirschsprung's disease (HSCR) is a congenital disorder characterized by the absence of enteric neural crest cells (ENCCs). LncRNA rhabdomyosarcoma 2-associated transcript (RMST) is essential for the growth and development of neuron. This study aimed to reveal the role of RMST in the pathogenesi...

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Detalles Bibliográficos
Autores principales: Zhou, Lingling, Zhi, Zhengke, Chen, Pingfa, Du, Chunxia, Wang, Binyu, Fang, Xiang, Tang, Weibing, Li, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936393/
https://www.ncbi.nlm.nih.gov/pubmed/35321017
http://dx.doi.org/10.3389/fped.2022.749107