Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model

Oligodendrocytes are implicated in amyotrophic lateral sclerosis pathogenesis and display transactive response DNA-binding protein-43 (TDP-43) pathological inclusions. To investigate the cell autonomous consequences of TDP-43 mutations on human oligodendrocytes, we generated oligodendrocytes from pa...

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Detalles Bibliográficos
Autores principales: Barton, Samantha K, Magnani, Dario, James, Owen G, Livesey, Matthew R, Selvaraj, Bhuvaneish T, James, Owain T, Perkins, Emma M, Gregory, Jenna M, Cleary, Elaine, Ausems, C Rosanne M, Carter, Roderick N Carter, Vasistha, Navneet A, Zhao, Chen, Burr, Karen, Story, David, Cardinali, Alessandra, Morton, Nicholas M, Hardingham, Giles E, Wyllie, David J A, Chandran, Siddharthan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936427/
https://www.ncbi.nlm.nih.gov/pubmed/35350711
http://dx.doi.org/10.1093/braincomms/fcab255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936427/
https://www.ncbi.nlm.nih.gov/pubmed/35350711
http://dx.doi.org/10.1093/braincomms/fcab255

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