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Antitumor activity of T cells secreting αCD133-αCD3 bispecific T-cell engager against cholangiocarcinoma

Cholangiocarcinoma (CCA) is a lethal cancer of bile duct epithelial cells with a high mortality rate and limited therapeutic options. An effective treatment is, therefore, urgently needed to improve treatment outcomes for these patients. To develop a new therapeutic option, we engineered T cells sec...

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Detalles Bibliográficos
Autores principales: Sangsuwannukul, Thanich, Supimon, Kamonlapat, Chieochansin, Thaweesak, Choomee, Kornkan, Sujjitjoon, Jatuporn, Junking, Mutita, Yenchitsomanus, Pa-thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936442/
https://www.ncbi.nlm.nih.gov/pubmed/35312724
http://dx.doi.org/10.1371/journal.pone.0265773