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FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics

Treadmilling protein filaments perform essential cellular functions by growing from one end while shrinking from the other, driven by nucleotide hydrolysis. Bacterial cell division relies on the primitive tubulin homolog FtsZ, a target for antibiotic discovery that assembles into single treadmilling...

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Detalles Bibliográficos
Autores principales: Ruiz, Federico M., Huecas, Sonia, Santos-Aledo, Alicia, Prim, Elena A., Andreu, José M., Fernández-Tornero, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936486/
https://www.ncbi.nlm.nih.gov/pubmed/35312677
http://dx.doi.org/10.1371/journal.pbio.3001497