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Lung cancer cells expressing a shortened CDK16 3′UTR escape senescence through impaired miR‐485‐5p targeting

Inducing senescence in cancer cells is an emerging strategy for cancer therapy. The dysregulation and mutation of genes encoding cyclin‐dependent kinases (CDKs) have been implicated in various human cancers. However, whether CDK can induce cancer cell senescence remains poorly understood. We observe...

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Detalles Bibliográficos
Autores principales: Jia, Qi, Xie, Baiyun, Zhao, Zhaozhao, Huang, Leihuan, Wei, Gang, Ni, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936527/
https://www.ncbi.nlm.nih.gov/pubmed/34687270
http://dx.doi.org/10.1002/1878-0261.13125