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Caspase-8: Friend or Foe in Bortezomib/Lenalidomide-Based Therapy for Myeloma

Antiproliferation and proapoptosis are two major molecular mechanisms of action of drugs used for the treatment of multiple myeloma. Proteasome inhibitors, such as bortezomib (PS-341), and immunomodulatory drugs (IMiDs), such as lenalidomide, are the two drug types approved for the treatment of myel...

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Detalles Bibliográficos
Autor principal: Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936587/
https://www.ncbi.nlm.nih.gov/pubmed/35321428
http://dx.doi.org/10.3389/fonc.2022.861709