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Slc6a20a Heterozygous and Homozygous Mutant Mice Display Differential Behavioral and Transcriptomic Changes

SLC6A20A is a proline and glycine transporter known to regulate glycine homeostasis and NMDA receptor (NMDAR) function in the brain. A previous study found increases in ambient glycine levels and NMDA receptor-mediated synaptic transmission in the brains of Slc6a20a-haploinsufficient mice, but it re...

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Detalles Bibliográficos
Autores principales: Kim, Junhyung, Roh, Junyeop Daniel, Kim, Seongbin, Kang, Hyojin, Bae, Mihyun, Kim, Eunjoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8936588/
https://www.ncbi.nlm.nih.gov/pubmed/35321029
http://dx.doi.org/10.3389/fnmol.2022.857820