The Essential Role of Rac1 Glucosylation in Clostridioides difficile Toxin B-Induced Arrest of G1-S Transition

Clostridioides difficile infection (CDI) in humans causes pseudomembranous colitis (PMC), which is a severe pathology characterized by a loss of epithelial barrier function and massive colonic inflammation. PMC has been attributed to the action of two large protein toxins, Toxin A (TcdA) and Toxin B...

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Detalles Bibliográficos
Autores principales: Petersen, Lara, Stroh, Svenja, Schöttelndreier, Dennis, Grassl, Guntram A., Rottner, Klemens, Brakebusch, Cord, Fahrer, Jörg, Genth, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937036/
https://www.ncbi.nlm.nih.gov/pubmed/35321078
http://dx.doi.org/10.3389/fmicb.2022.846215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937036/
https://www.ncbi.nlm.nih.gov/pubmed/35321078
http://dx.doi.org/10.3389/fmicb.2022.846215

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