Shank promotes action potential repolarization by recruiting BK channels to calcium microdomains

Mutations altering the scaffolding protein Shank are linked to several psychiatric disorders, and to synaptic and behavioral defects in mice. Among its many binding partners, Shank directly binds CaV1 voltage activated calcium channels. Here, we show that the Caenorhabditis elegans SHN-1/Shank promo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Luna, Zhao, Jian, Ardiel, Evan, Hall, Qi, Nurrish, Stephen, Kaplan, Joshua M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937234/
https://www.ncbi.nlm.nih.gov/pubmed/35266450
http://dx.doi.org/10.7554/eLife.75140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937234/
https://www.ncbi.nlm.nih.gov/pubmed/35266450
http://dx.doi.org/10.7554/eLife.75140

Ejemplares similares