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Shank promotes action potential repolarization by recruiting BK channels to calcium microdomains
Mutations altering the scaffolding protein Shank are linked to several psychiatric disorders, and to synaptic and behavioral defects in mice. Among its many binding partners, Shank directly binds CaV1 voltage activated calcium channels. Here, we show that the Caenorhabditis elegans SHN-1/Shank promo...
Autores principales: | Gao, Luna, Zhao, Jian, Ardiel, Evan, Hall, Qi, Nurrish, Stephen, Kaplan, Joshua M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8937234/ https://www.ncbi.nlm.nih.gov/pubmed/35266450 http://dx.doi.org/10.7554/eLife.75140 |
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