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Immunoglobulin G1 Fc glycosylation as an early hallmark of severe COVID-19

BACKGROUND: Immunoglobulin G1 (IgG1) effector functions are impacted by the structure of fragment crystallizable (Fc) tail-linked N-glycans. Low fucosylation levels on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein-specific IgG1 has been described as a hallmark of sev...

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Detalles Bibliográficos
Autores principales: Pongracz, Tamas, Nouta, Jan, Wang, Wenjun, van Meijgaarden, Krista E., Linty, Federica, Vidarsson, Gestur, Joosten, Simone A., Ottenhoff, Tom H.M., Hokke, Cornelis H., de Vries, Jutte J.C., Arbous, Sesmu M., Roukens, Anna H.E., Wuhrer, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938159/
https://www.ncbi.nlm.nih.gov/pubmed/35334306
http://dx.doi.org/10.1016/j.ebiom.2022.103957