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Evaluation of Metformin Hydrochloride Tailoring Bilosomes as an Effective Transdermal Nanocarrier

INTRODUCTION: Metformin hydrochloride (metformin HCL), a first-line drug treating diabetes type II, was known to cause severe gastritis, so seeking a non-oral dosage form was the new trend. Bilosomes are bilayer nano-vesicles of non-ionic surfactants embodying bile salts. In our study, bilosomes wer...

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Detalles Bibliográficos
Autores principales: Salem, Heba F, Nafady, Mohammed M, Ali, Adel A, Khalil, Nermeen M, Elsisi, Amani A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938169/
https://www.ncbi.nlm.nih.gov/pubmed/35330695
http://dx.doi.org/10.2147/IJN.S345505