Whole-genome risk prediction of common diseases in human preimplantation embryos

Preimplantation genetic testing (PGT) of in-vitro-fertilized embryos has been proposed as a method to reduce transmission of common disease; however, more comprehensive embryo genetic assessment, combining the effects of common variants and rare variants, remains unavailable. Here, we used a combina...

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Detalles Bibliográficos
Autores principales: Kumar, Akash, Im, Kate, Banjevic, Milena, Ng, Pauline C., Tunstall, Tate, Garcia, Geronimo, Galhardo, Luisa, Sun, Jiayi, Schaedel, Oren N., Levy, Brynn, Hongo, Donna, Kijacic, Dusan, Kiehl, Michelle, Tran, Nam D., Klatsky, Peter C., Rabinowitz, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938270/
https://www.ncbi.nlm.nih.gov/pubmed/35314819
http://dx.doi.org/10.1038/s41591-022-01735-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938270/
https://www.ncbi.nlm.nih.gov/pubmed/35314819
http://dx.doi.org/10.1038/s41591-022-01735-0

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