The miR-23b/27b/24-1 Cluster Inhibits Hepatic Fibrosis by Inactivating Hepatic Stellate Cells

BACKGROUND & AIMS: Hepatic fibrosis is characterized by hepatic stellate cell (HSC) activation and transdifferentiation-mediated extracellular matrix (ECM) deposition, which both contribute to cirrhosis. However, no antifibrotic regimen is available in the clinic. microRNA-23b/27b/24-1 cluster i...

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Detalles Bibliográficos
Autores principales: Wan, Lin-Yan, Peng, Hu, Ni, Yi-Ran, Jiang, Xue-Ping, Wang, Jiao-Jiao, Zhang, Yan-Qiong, Ma, Lan, Li, Rui, Han, Lin, Tan, Yong, Li, Jun-Ming, Cai, Wen-Li, Yuan, Wen-Fang, Liang, Jia-Jie, Huang, Lu, Wu, Xu, Zhou, Quan, Cheng, Qi-Ni, Yang, Xue, Liu, Meng-Yuan, Ai, Wen-Bing, Liu, Chang-Bai, Zhang, Hongbing, Wu, Jiang-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938281/
https://www.ncbi.nlm.nih.gov/pubmed/35093591
http://dx.doi.org/10.1016/j.jcmgh.2022.01.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938281/
https://www.ncbi.nlm.nih.gov/pubmed/35093591
http://dx.doi.org/10.1016/j.jcmgh.2022.01.016

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