Rs1h(−/y) exon 3-del rat model of X-linked retinoschisis with early onset and rapid phenotype is rescued by RS1 supplementation

Animal models of X-linked juvenile retinoschisis (XLRS) are valuable tools for understanding basic biochemical function of retinoschisin (RS1) protein and to investigate outcomes of preclinical efficacy and toxicity studies. In order to work with an eye larger than mouse, we generated and characteri...

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Detalles Bibliográficos
Autores principales: Zeng, Yong, Qian, Haohua, Campos, Maria Mercedes, Li, Yichao, Vijayasarathy, Camasamudram, Sieving, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938309/
https://www.ncbi.nlm.nih.gov/pubmed/34548657
http://dx.doi.org/10.1038/s41434-021-00290-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938309/
https://www.ncbi.nlm.nih.gov/pubmed/34548657
http://dx.doi.org/10.1038/s41434-021-00290-6

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