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A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oogenesis and wing development

Metazoans have evolved various quality control mechanisms to cope with cellular stress inflicted by external and physiological conditions. ATF4 is a major effector of the integrated stress response, an evolutionarily conserved pathway that mediates adaptation to various cellular stressors. Loss of f...

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Detalles Bibliográficos
Autores principales: Vasudevan, Deepika, Katow, Hidetaka, Huang, Huai-Wei, Tang, Grace, Ryoo, Hyung Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938396/
https://www.ncbi.nlm.nih.gov/pubmed/34919148
http://dx.doi.org/10.1242/dmm.049119