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Transposon insertional mutagenesis of diverse yeast strains suggests coordinated gene essentiality polymorphisms
Due to epistasis, the same mutation can have drastically different phenotypic consequences in different individuals. This phenomenon is pertinent to precision medicine as well as antimicrobial drug development, but its general characteristics are largely unknown. We approach this question by genome-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938418/ https://www.ncbi.nlm.nih.gov/pubmed/35314699 http://dx.doi.org/10.1038/s41467-022-29228-1 |