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BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease

Tubulointerstitial fibrosis (TIF) is involved in the development of diabetic kidney disease (DKD). Transforming growth factor β1 (TGF-β1) is involved in the extensive fibrosis of renal tissue by facilitating the partial epithelial-mesenchymal transition (EMT), increasing the synthesis of extracellul...

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Detalles Bibliográficos
Autores principales: Peng, Wei, Zhou, Xingcheng, Xu, Tingting, Mao, Yanwen, Zhang, Xiaohuan, Liu, Huiming, Liang, Luqun, Liu, Lingling, Liu, Lirong, Xiao, Ying, Zhang, Fan, Li, Shuang, Shi, Mingjun, Zhou, Yuxia, Tang, Lei, Wang, Yuanyuan, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938433/
https://www.ncbi.nlm.nih.gov/pubmed/35314669
http://dx.doi.org/10.1038/s41419-022-04529-x