RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning

The bidirectional movement of lysosomes on microtubule tracks regulates their whole-cell spatial arrangement. Arl8b, a small GTP-binding (G) protein, promotes lysosome anterograde trafficking mediated by kinesin-1. Herein, we report an Arl8b effector, RUFY3, which regulates the retrograde transport...

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Detalles Bibliográficos
Autores principales: Kumar, Gaurav, Chawla, Prateek, Dhiman, Neha, Chadha, Sanya, Sharma, Sheetal, Sethi, Kanupriya, Sharma, Mahak, Tuli, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938454/
https://www.ncbi.nlm.nih.gov/pubmed/35314681
http://dx.doi.org/10.1038/s41467-022-29077-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938454/
https://www.ncbi.nlm.nih.gov/pubmed/35314681
http://dx.doi.org/10.1038/s41467-022-29077-y

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