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Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures

Parkinson’s disease (PD) is a multi-stage neurodegenerative disorder with largely unknown etiology. Recent findings have identified PD-associated autoimmune features including roles for T cells. To further characterize the role of T cells in PD, we performed RNA sequencing on PBMC and peripheral CD4...

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Detalles Bibliográficos
Autores principales: Dhanwani, Rekha, Lima-Junior, João Rodrigues, Sethi, Ashu, Pham, John, Williams, Gregory, Frazier, April, Xu, Yaqian, Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Alcalay, Roy N., Peters, Bjoern, Sulzer, David, Arlehamn, Cecilia S. Lindestam, Sette, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938520/
https://www.ncbi.nlm.nih.gov/pubmed/35314697
http://dx.doi.org/10.1038/s41531-022-00282-2