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Progression of type 1 diabetes from latency to symptomatic disease is predicted by distinct autoimmune trajectories

Development of islet autoimmunity precedes the onset of type 1 diabetes in children, however, the presence of autoantibodies does not necessarily lead to manifest disease and the onset of clinical symptoms is hard to predict. Here we show, by longitudinal sampling of islet autoantibodies (IAb) to in...

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Detalles Bibliográficos
Autores principales: Kwon, Bum Chul, Anand, Vibha, Achenbach, Peter, Dunne, Jessica L., Hagopian, William, Hu, Jianying, Koski, Eileen, Lernmark, Åke, Lundgren, Markus, Ng, Kenney, Toppari, Jorma, Veijola, Riitta, Frohnert, Brigitte I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938551/
https://www.ncbi.nlm.nih.gov/pubmed/35314671
http://dx.doi.org/10.1038/s41467-022-28909-1