Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway

Leucine-rich α-2-glycoprotein 1 (LRG1) is a secreted glycoprotein that under physiological conditions is produced predominantly by the liver. In disease, its local induction promotes pathogenic neovascularisation while its inhibition leads to reduced dysfunctional angiogenesis. Here we examine the r...

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Detalles Bibliográficos
Autores principales: Dritsoula, Athina, Dowsett, Laura, Pilotti, Camilla, O’Connor, Marie N., Moss, Stephen E., Greenwood, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938720/
https://www.ncbi.nlm.nih.gov/pubmed/35318338
http://dx.doi.org/10.1038/s41598-022-08516-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938720/
https://www.ncbi.nlm.nih.gov/pubmed/35318338
http://dx.doi.org/10.1038/s41598-022-08516-2

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