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Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in Type 1 Diabetes

Type 1 Diabetes (T1D) is an autoimmune disease in which immune cells destroy insulin-producing beta cells. The etiology of this complex disease is dependent on the interplay of multiple heterogeneous cell types in the pancreatic environment. Here, we provide a single-cell atlas of pancreatic islets...

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Detalles Bibliográficos
Autores principales: Fasolino, Maria, Schwartz, Gregory W., Patil, Abhijeet R., Mongia, Aanchal, Golson, Maria L., Wang, Yue J., Morgan, Ashleigh, Liu, Chengyang, Schug, Jonathan, Liu, Jinping, Wu, Minghui, Traum, Daniel, Kondo, Ayano, May, Catherine L., Goldman, Naomi, Wang, Wenliang, Feldman, Michael, Moore, Jason H., Japp, Alberto S., Betts, Michael R., Faryabi, Robert B., Naji, Ali, Kaestner, Klaus H., Vahedi, Golnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938904/
https://www.ncbi.nlm.nih.gov/pubmed/35228745
http://dx.doi.org/10.1038/s42255-022-00531-x