Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion

[Image: see text] Background: Lower survival rates for many cancer types correlate with changes in nuclear size/scaling in a tumor-type/tissue-specific manner. Hypothesizing that such changes might confer an advantage to tumor cells, we aimed at the identification of commercially available compounds...

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Detalles Bibliográficos
Autores principales: Tollis, Sylvain, Rizzotto, Andrea, Pham, Nhan T., Koivukoski, Sonja, Sivakumar, Aishwarya, Shave, Steven, Wildenhain, Jan, Zuleger, Nikolaj, Keys, Jeremy T., Culley, Jayne, Zheng, Yijing, Lammerding, Jan, Carragher, Neil O., Brunton, Valerie G., Latonen, Leena, Auer, Manfred, Tyers, Mike, Schirmer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938924/
https://www.ncbi.nlm.nih.gov/pubmed/35199530
http://dx.doi.org/10.1021/acschembio.2c00004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938924/
https://www.ncbi.nlm.nih.gov/pubmed/35199530
http://dx.doi.org/10.1021/acschembio.2c00004

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