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Engineering Strategies to Overcome the Stability–Function Trade-Off in Proteins

[Image: see text] In addition to its biological function, the stability of a protein is a major determinant for its applicability. Unfortunately, engineering proteins for improved functionality usually results in destabilization of the protein. This so-called stability–function trade-off can be expl...

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Detalles Bibliográficos
Autores principales: Teufl, Magdalena, Zajc, Charlotte U., Traxlmayr, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938945/
https://www.ncbi.nlm.nih.gov/pubmed/35258287
http://dx.doi.org/10.1021/acssynbio.1c00512