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Selective α-Methylation of Aryl Ketones Using Quaternary Ammonium Salts as Solid Methylating Agents
[Image: see text] We describe the use of phenyl trimethylammonium iodide (PhMe(3)NI) as an alternative methylating agent for introducing a CH(3) group in α-position to a carbonyl group. Compared to conventional methylating agents, quaternary ammonium salts have the advantages of being nonvolatile, n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938946/ https://www.ncbi.nlm.nih.gov/pubmed/35253422 http://dx.doi.org/10.1021/acs.joc.1c03158 |