Synthesis of Chiral Tetrahydro-3-benzazepine Motifs by Iridium-Catalyzed Asymmetric Hydrogenation of Cyclic Ene-carbamates

[Image: see text] A highly efficient N,P-ligated iridium complex is presented for the simple preparation of chiral tetrahydro-3-benzazepine motifs by catalytic asymmetric hydrogenation. Substrates bearing both 1-aryl and 1-alkyl substituents were smoothly converted to the corresponding hydrogenated...

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Detalles Bibliográficos
Autores principales: Peters, Bram B. C., Andersson, Pher G., Ruchirawat, Somsak, Ieawsuwan, Winai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938950/
https://www.ncbi.nlm.nih.gov/pubmed/35238569
http://dx.doi.org/10.1021/acs.orglett.2c00362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938950/
https://www.ncbi.nlm.nih.gov/pubmed/35238569
http://dx.doi.org/10.1021/acs.orglett.2c00362

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