Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense

Host interferons (IFNs) powerfully restrict viruses through the action of several hundred IFN-stimulated gene (ISG) products, many of which remain uncharacterized. Here, using RNAi screening, we identify several ISG restriction factors with previously undescribed contributions to IFN-mediated defens...

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Detalles Bibliográficos
Autores principales: Fernbach, Sonja, Spieler, Eva E., Busnadiego, Idoia, Karakus, Umut, Lkharrazi, Anouk, Stertz, Silke, Hale, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939003/
https://www.ncbi.nlm.nih.gov/pubmed/35320721
http://dx.doi.org/10.1016/j.celrep.2022.110549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939003/
https://www.ncbi.nlm.nih.gov/pubmed/35320721
http://dx.doi.org/10.1016/j.celrep.2022.110549

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