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Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
Host interferons (IFNs) powerfully restrict viruses through the action of several hundred IFN-stimulated gene (ISG) products, many of which remain uncharacterized. Here, using RNAi screening, we identify several ISG restriction factors with previously undescribed contributions to IFN-mediated defens...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Author(s).
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939003/ https://www.ncbi.nlm.nih.gov/pubmed/35320721 http://dx.doi.org/10.1016/j.celrep.2022.110549 |