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Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

BACKGROUND: Field cancerization is the process in which a population of normal or pre-malignant cells is affected by oncogenic alterations leading to progressive molecular changes that drive malignant transformation. Aberrant DNA methylation has been implicated in early cancer development in non-sma...

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Detalles Bibliográficos
Autores principales: Wang, Qiushi, Wu, Libo, Yu, Jiaxing, Li, Guanghua, Zhang, Pengfei, Wang, Haozhe, Shao, Lin, Liu, Jinying, Shen, Weixi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939144/
https://www.ncbi.nlm.nih.gov/pubmed/35313869
http://dx.doi.org/10.1186/s12920-022-01192-1