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Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer
BACKGROUND: Field cancerization is the process in which a population of normal or pre-malignant cells is affected by oncogenic alterations leading to progressive molecular changes that drive malignant transformation. Aberrant DNA methylation has been implicated in early cancer development in non-sma...
Autores principales: | Wang, Qiushi, Wu, Libo, Yu, Jiaxing, Li, Guanghua, Zhang, Pengfei, Wang, Haozhe, Shao, Lin, Liu, Jinying, Shen, Weixi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939144/ https://www.ncbi.nlm.nih.gov/pubmed/35313869 http://dx.doi.org/10.1186/s12920-022-01192-1 |
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