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SIRPα and PD1 expression on tumor-associated macrophage predict prognosis of intrahepatic cholangiocarcinoma

BACKGROUND: The phagocytosis checkpoints of CD47/SIRPα, PD1/PDL1, CD24/SIGLEC10, and MHC/LILRB1 have shown inhibited phagocytosis of macrophages in distinct tumors. However, phagocytosis checkpoints and their therapeutic significance remain largely unknown in intrahepatic cholangiocarcinoma (ICC) pa...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Yan, Meimei, Li, Wei, Xu, Linping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939174/
https://www.ncbi.nlm.nih.gov/pubmed/35317832
http://dx.doi.org/10.1186/s12967-022-03342-6