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An evidence appraisal of heart organoids in a dish and commensurability to human heart development in vivo
Stem-cell derived in vitro cardiac models have provided profound insights into mechanisms in cardiac development and disease. Efficient differentiation of specific cardiac cell types from human pluripotent stem cells using a three-step Wnt signaling modulation has been one of the major discoveries t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939187/ https://www.ncbi.nlm.nih.gov/pubmed/35317745 http://dx.doi.org/10.1186/s12872-022-02543-7 |