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Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity

A damaging inflammatory response is implicated in the pathogenesis of severe coronavirus disease 2019 (COVID-19), but mechanisms contributing to this response are unclear. In two prospective cohorts, early non-neutralizing, afucosylated IgG antibodies specific to severe acute respiratory syndrome co...

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Detalles Bibliográficos
Autores principales: Chakraborty, Saborni, Gonzalez, Joseph C., Sievers, Benjamin L., Mallajosyula, Vamsee, Chakraborty, Srijoni, Dubey, Megha, Ashraf, Usama, Cheng, Bowie Yik-Ling, Kathale, Nimish, Tran, Kim Quyen Thi, Scallan, Courtney, Sinnott, Aanika, Cassidy, Arianna, Chen, Steven T., Gelbart, Terri, Gao, Fei, Golan, Yarden, Ji, Xuhuai, Kim-Schulze, Seunghee, Prahl, Mary, Gaw, Stephanie L., Gnjatic, Sacha, Marron, Thomas U., Merad, Miriam, Arunachalam, Prabhu S., Boyd, Scott D., Davis, Mark M., Holubar, Marisa, Khosla, Chaitan, Maecker, Holden T., Maldonado, Yvonne, Mellins, Elizabeth D., Nadeau, Kari C., Pulendran, Bali, Singh, Upinder, Subramanian, Aruna, Utz, Paul J., Sherwood, Robert, Zhang, Sheng, Jagannathan, Prasanna, Tan, Gene S., Wang, Taia T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939764/
https://www.ncbi.nlm.nih.gov/pubmed/35040666
http://dx.doi.org/10.1126/scitranslmed.abm7853