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Broad anti-SARS-CoV-2 antibody immunity induced by heterologous ChAdOx1/mRNA-1273 vaccination

Heterologous prime-boost immunization strategies have the potential to augment COVID-19 vaccine efficacy. We longitudinally profiled SARS-CoV-2 spike (S)-specific serological and memory B cell (MBC) responses in individuals receiving either homologous (ChAdOx1:ChAdOx1) or heterologous (ChAdOx1:mRNA-...

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Detalles Bibliográficos
Autores principales: Kaku, Chengzi I., Champney, Elizabeth R., Normark, Johan, Garcia, Marina, Johnson, Carl E., Ahlm, Clas, Christ, Wanda, Sakharkar, Mrunal, Ackerman, Margaret E., Klingström, Jonas, Forsell, Mattias N. E., Walker, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939765/
https://www.ncbi.nlm.nih.gov/pubmed/35143256
http://dx.doi.org/10.1126/science.abn2688